Activated B Complex aids in the metabolism of carbohydrates.

Helps maintain nervous system function and supports a healthy stress response in the body and emotional wellbeing.

Contains B5 and the active form of B6 (pyridoxal 5-phosphate monohydrate) to support healthy adrenal gland function. B vitamins support the health and production of red blood cells and supports cardiovascular system health.

Contains mecobalamin (co methylcobalamin), the active form of vitamin B12. Other forms of vitamin B12, such as cyanocobalamin, need to be converted to co-methylcobalamin for use in the body.

Contains methylfolate (levomefolic acid), the active form of folate.

Methylfolate and vitamin B12 support memory and cognitive function. Methylfolate also helps reduce homocysteine levels.

• Thiamine hydrochloride 25mg (equiv. Thiamine (vitamin B1) 22.3mg)
• Riboflavin sodium phosphate 25mg (equiv. Riboflavin (vitamin B2) 18.3mg)
• Nicotinamide 25mg
• Calcium pantothenate 25mg (equiv. Pantothenic acid (vitamin B5) 22.9mg)
• Pyridoxal 5-phosphate monohydrate 25mg equiv. Pyridoxine (vitamin B6) 15.95mg)
• Levomefolate glucosamine (Quatrefolic) 842 micrograms (equiv. Levomefolic acid (5-MTHF) 400mcg)
• Mecobalamin (co-methylcobalamin) (vitamin B12) 400mcg

Adults and children over 12 years: Take 1 capsule daily, with food, or as directed by your health professional.

Does not contain egg, milk, peanut, soy, tree nuts, animal products, gluten, lactose or artificial colours, flavours or preservatives.

WARNINGS:

Advise your doctor of any medicine you take during pregnancy, particularly in your first trimester. Vitamin supplements should not replace a balanced diet.

DRUG INTERACTIONS:

Caution with cholestyramine and colestipol (hypolipidaemic agents) - may decrease the absorption of vitamin B3 and folate. Separate dose by at least 4-6 hours.

Caution with phenobarbital and phenytoin (anticonvulsants) - high doses of vitamin B6 or folate can decrease their efficacy. Monitor.

Caution with L-Dopa - vitamin B6 increases the peripheral metabolism of levodopa and may lower levodopa levels for CNS penetration, resulting in reduced levodopa effects. The effect of pyridoxine is prevented by administration of a dopa-decarboxylase inhibitor (e.g. benserazide, carbidopa) with levodopa, as is common clinical practice.

Caution with antiepileptic and anticonvulsant medications - folic acid may reduce serum levels of these medications. Patients should take folate only under the supervision of a health professional.

Caution with methotrexate (folic acid antagonist) - co-administrate with folate may reduce the effects. Patients should take folate only under the supervision of a health professional.

Caution with tetracycline hydrochloride (antibiotic) - B vitamins may reduce drug bioavailability. Separate dose by at least 2 hours.

Several medications may deplete folate status, including trimethoprim (antibiotic), pyrimethamine (antimalarial), triamterene (blood pressure), sulfasalazine (for ulcerative colitis) and oral contraceptives.

Several medications can decrease the absorption of vitamin B12 or increase the risk of deficiency, such as acid-suppressing medications (proton-pump inhibitors e.g. omeprazole and histamine2 (h2)-receptor antagonists), metformin (hypoglycaemic), oral contraceptives, neomycin (antibiotic) and colchicine (anti-gout).

CAUTIONS:

B vitamins are stimulatory in nature. To avoid any sleep interferance, avoid taking before bed.

Taking at night may result in more vivid dreams (vitamin B6).

SIDE EFFECTS:

Supplemental B vitamins may cause nausea or mild gastrointestinal upset if taken on an empty stomach. Best taken with food to reduce risk.

Riboflavin can impart a bright yellow colour to urine.

COMPANION PRODUCTS:

Magnesium Citrate 900

Mind Ease

Stress Ease

Ubiquinol 150mg